Eighteen species of the frog genus Phrynobatrachus are recognized from Cameroon. We describe a new species from Mt. Nlonako in the Littoral Province of Western Cameroon. It was recorded during a six-year amphibian inventory at Mt. Nlonako and is known only from the type locality within a submontane rain forest at an altitude of approximately 450 m. Because of the low number of captures over the six-year period, Phrynobatrachus sp. nov. is considered a secretive leaf litter species. Diagnostic characters are a smooth skin texture, a distinct tympanum, rudimentary webbing, white spots on the lips extending to the hands and along the flanks, and a white interorbital line.